When your body sleeps your immune system awakens!
Along with exercise and nutrition, sleep is one of the three pillars of health. Yet it is often the most misunderstood and the least prioritized of the three. This is often because it is the hardest to control.
One of the questions we have been asked the most often during the coronavirus quarantine is "How do I improve my sleep?" It seems that, along with prioritizing health, people want to sleep better - especially as the stress of COVID-19 is causing many new sleep disturbances not previously experienced.
Studies have shown that people who miss out on quality sleep or fall short of adequate hours of sleep are more likely to get sick after being exposed to a virus. Lack of sleep can also negatively impact how quickly you recover if you do get sick. In fact, there are a lot of adverse side effects to sleep deprivation.
While you’re sleeping your immune system awakens and releases protective immune proteins called cytokines. Certain cytokines need to increase when you have an infection, inflammation, or when you're under stress, and sleep deprivation may decrease production of these protective cytokines. In addition, infection-fighting antibodies and cells are reduced during periods when you don't get enough sleep.
If you are worried about protecting yourself against viruses and giving your body the best chance to fight off infection then you need to ensure adequate hours of good quality, restorative sleep every night. By prioritising sleep, you can make your immune system more efficient, resulting in a healthier body that is more able to fight off infection and disease.
So what can you take to help you sleep well and encourage your immune system to work hard protecting you against infection during the night?
PrizMAG, a pure magnesium bisglycinate capsule with no fillers, is highly beneficial for people looking to increase not only the number of hours they sleep but also the quality of their night-time sleeping patterns. Additionally, it can play an important role in immune regulation, prompting white blood cells like macrophages to activate and remove foreign bodies at sites of infection.
PrizMAG consists of 1 magnesium molecule and two glycine amino acids. Together they are a dynamic powerhouse combination that can help you to not just fall asleep more readily, but to stay asleep throughout the night and feel more rested in the morning. This is because both glycine and magnesium have sleep-inducing properties. Additionally, glycine has been shown to improve immune regulation.
Magnesium is known as 'nature's tranquiliser' and has a calming relaxing effect on the body in general so it can be invaluable if you are suffering from tension or stress that might be keeping you from getting to sleep and staying asleep.
As for glycine, it holds its own when it comes to a good night’s sleep: in one study, volunteers who complained of sleep problems took either three grams of glycine or a placebo before going to sleep and were then evaluated when they woke up. The glycine participants reported significant improvements after they woke up, including less fatigue, more liveliness, more peppiness, and greater mental clarity.
In another study, 10 healthy males who had no sleep complaints were evaluated for sleep quality spending their usual time in bed, which was an average of 7.3 hours. These participants were then either given a placebo or three grams of glycine and reduced their time in bed to 5.5 hours for three consecutive nights. At the end of the study, researchers reported glycine was associated with significant improvements in fatigue, daytime sleepiness, and daytime performance after nights where sleep was restricted.
Four capsules of PrizMAG will give you the three grams of glycine tested in the study plus close to your full RDA of magnesium (though many people find they feel better with higher dosages as our bodies burn through magnesium at an extreme rate, especially during a stressful time like COVID-19 induced quarantine). There is no better combination for sleep and immunity than PrizMAG pure magnesium bisglycinate!
The role of glycine in regulated cell death, Published in final edited form as:
Cell Mol Life Sci. 2016 Jun; 73(11-12): 2285–2308. doi: 10.1007/s00018-016-2201-6 (Accessed March 12th 2020)
A novel physiological mechanism of glycine-induced immunomodulation: Na+-coupled amino acid transporter currents in cultured brain macrophages, J Physiol. 2004 Aug 15; 559(Pt 1): 35–40. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1665071/ (Accessed March 12th 2020)
Mayo Clinic (2018). Lack of sleep: Can it make you sick?, Eric J. Olson, MD, Nov 28th 2018, https://www.mayoclinic.org/diseases-conditions/insomnia/expert-answers/lack-of-sleep/faq-20057757 (Accessed March 12th 2020)
Harvard Medical School (2008), Healthy Sleep, Why Sleep Matters, http://healthysleep.med.harvard.edu/healthy/matters (Accessed March 12th 2020)
Human immune system during sleep, Am J Clin Exp Immunol. 2017; 6(6): 92–96. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768894/ (Accessed March 12th 2020)
Sleep and Biological Rhythms http://doi.org/10.1111/j.1479-8425.2006.00193.x (Accessed March 12th 2020)
Sleep in Elite Athletes and Nutritional Interventions to Enhance Sleep PMCID: PMC4008810 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008810 (Accessed March 12th 2020)