COVID-19 Stress

COVID-19 went from faint background noise in our news feeds to turning our world upside down in only a few short months. If you’re finding yourself feeling stressed, overwhelmed, or having a hard time coping with the new normal, rest assured: You are not alone. Here are two big ways magnesium can help create some calm amid the current chaos:

Stress & Anxiety Relief

Magnesium affects the part of your brain called the hypothalamus, which aids in regulating your adrenal and pituitary glands. [1] These glands produce two stress hormones you’re probably familiar with: Adrenaline and Cortisol. Both hormones are crucial to your wellbeing when you’re in a dangerous situation or in pure survival mode, but when your body is low in magnesium, so is the threshold for the activation of these stress hormones. This leads to feelings of intense anxiety in situations that normally wouldn’t be overly distressing. Are you regularly going into stress-overdrive before heading out to buy groceries? Magnesium-deficiency may be a contributing factor.

Here’s the kicker: Stress can zap your body’s existing magnesium stores, which leads to a vicious cycle of stress leading to more stress. [2] Since a global pandemic can be deemed a “stress-inducing situation”, we may safely assume our bodies are quickly using up their magnesium stores. 

And now for the good news: Supplementing with magnesium can stop this stress cycle in its tracks! Multiple studies done on the efficacy of magnesium in stress management have concluded that magnesium supplementation effectively reduces mild to moderate anxiety, while significantly minimizing the impact of stress on the body. [1, 3, 4]


During times of stress, our sleep can be one of the first things to suffer. If you're having trouble sleeping well during these times of uncertainty, magnesium can help here, too. Studies show magnesium supplementation can be highly effective in reducing symptoms of insomnia, making it easier for you to fall asleep at night, while promoting longer, sounder, better-quality rest. [5,6] Sleep is also a crucial part of keeping your immune system in good working order [7], so improving your quality of sleep with magnesium is a win/win situation.


Not all magnesium supplements are created equal, and that’s why the type of magnesium supplement you choose is important. MAG365 BF contains an ionic form of magnesium, making it the most bioavailable and absorbable form of magnesium on the market.

And there’s another reason MAG365 BF is so relevant to our current situation: It is ionic magnesium with a healthy side of vitamin D3 and zinc. This is important because vitamin D3 and zinc are big players in a healthy immune system. 

A recent study suggests preventing vitamin D deficiency may provide benefit in those exposed to COVID-19 [8], as it has been shown to help signal the increased production of anti-inflammatory molecules while decreasing the production of pro-inflammatory molecules that may cause acute respiratory distress syndrome. [8, 9, 10]  Moreover, studies have reported associations between vitamin D deficiency and increased risk of infection [9], so having vitamin D3 added to your magnesium supplement is an incredibly helpful bonus.

Zinc, of course, is a superstar mineral when it comes to inhibiting and shortening viruses [11]. There isn’t any concrete evidence in its efficacy against COVID-19, but previous studies have shown it to be effective in reducing the length and severity of other types of coronavirus. [11, 12]

If you’re looking to reduce the stress, anxiety, and sleeplessness commonly experienced during this pandemic — while simultaneously boosting your immune system — MAG365 BF may be right for you. 


  1. Sartori, SB. (2012). Magnesium deficiency induces anxiety and HPA axis dysregulation: modulation by therapeutic drug treatment, Neuropharmacology
  2. Seelig, MS. (1994). Consequences of magnesium deficiency on the enhancement of stress reactions; preventive and therapeutic implications (a review). J Am Coll Nutr. 13(5):429-46.
  3. Tarasov, EA. (2015). Magnesium deficiency and stress: Issues of their relationship, diagnostic tests, and approaches to therapy, Ter Arkh.
  4. Boyle, N. (2017). The Effects of Magnesium Supplementation on Subjective Anxiety and Stress—A Systematic Review, Nutrients, 9(5): 429
  5. Depoortere, H. (1993). Effects of a magnesium-deficient diet on sleep organization in rats, Neuropsychobiology, 27(4):237-45
  6. Abbasi, B. (2012). The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial, J Res Med Sci., 17(12):1161-9
  7. Besedovsky, L. (2012). Sleep and immune function, Pflugers Arch, 463(1): 121–137
  8. Laird, E. (2020). Vitamin D deficiency in Ireland – implications for COVID-19, The Irish Longitudinal Study on Ageing (TILDA), 2 
  9. Jolliffe, D. (2012). Vitamin D in the Prevention of Acute Respiratory Infection: Systematic Review of Clinical Studies, J Steroid Biochem Mol Biol
  10. Sloka, S. (2012). Predominance of Th2 Polarization by Vitamin D Through a STAT6-dependent Mechanism, J Neuroinflammation
  11. Singh, M. (2013). Zinc for the common cold, Cochrane Database of Systematic Reviews
  12. Te Velthuis, J. (2010). Zn(2+) Inhibits Coronavirus and Arterivirus RNA Polymerase Activity in Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture, PLoS Pathog.
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